Protective Effect of Erythropoietin on Renal Injury Induced by Acute Exhaustive Exercise in the Rat

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چکیده

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Protective effect of erythropoietin on renal injury induced by acute exhaustive exercise in the rat.

We investigated the protective effect of Erythropoietin (EPO) analogue rHuEPO on renal injury induced by acute exhaustive exercise in the rat. Rats were randomly allocated to one of 3 groups: normal control (C), exhaustive exercise test (ET) and EPO pre-treatment (rHuEPO 2 000 U/kg) plus ET (EPO+ET). Compared with controls, animals in the ET group had increased serum urea nitrogen, serum creati...

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Protective effect of Erythropoietin on renal injury induced in rats by four weeks of exhaustive exercise

BACKGROUND The protective effect of Erythropoietin (EPO) analogue rHuEPO on acute renal injury induced by exhaustive exercise had been reported. The purpose of this study is to probe into the protective effect of EPO on chronic renal injury induced by repeated exhaustive exercise for four weeks. METHODS Eighty adult male Sprague-Dawley rats were used in this experiment. The animals were rando...

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Objective(s): Cardiotoxicity is one of the major consequences in carbon monoxide poisoning. Following our previous work, in this study we aimed to define the myocardium changes induced by carbon monoxide (CO) intoxication and evaluate erythropoietin (EPO) effect on CO cardiotoxicity in rat. Materials and Methods:  Severe carbon monoxide toxicity induced by 3000 ppm CO in Wistar rat.  EPO was ad...

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ژورنال

عنوان ژورنال: International Journal of Sports Medicine

سال: 2010

ISSN: 0172-4622,1439-3964

DOI: 10.1055/s-0030-1265205